Question: Using the two given starting materials, outline methods for the selective (ie major product) synthesis of each of the two alkene isomers of the product

Using the two given starting materials, outline methods for the selective (ie major product) synthesis of each of the two alkene isomers of the product (ie the two drawn). That this will require two sysntheses.

Starting Materials i om OH Products

Starting Materials i om OH Products

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To selectively synthesize each alkene isomer from the given starting materials we need to consider the elimination reaction pathways and the conditions that favor the formation of each isomer The two main methods for forming alkenes from alcohols are the E1 unimolecular elimination and E2 bimolecular elimination reactions Heres a stepbystep outline for synthesizing each isomer Synthesis of the First Alkene Isomer 1 Starting Material Use the ester ethyl ester from the starting material 2 Convert Alcohol to a Leaving Group Convert the alcohol to a good leaving group using a strong acid like sulfuric acid HSO This will form an alkyl sulfate intermediate 3 E1 Elimination Reaction Use a strongly acidic condition ... View full answer

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