Question: 1. A scientist is developing new microsatellite loci for analyzing the genetic diversity in a species of endangered frogs. What two characteristics will make a

1. A scientist is developing new microsatellite loci for analyzing the genetic diversity in a species of endangered frogs. What two characteristics will make a genomic DNA sequence suitable to use as a microsatellite locus for DNA fingerprinting?
2. For DNA fingerprinting in a paternity dispute the DNA profiles of STR loci A and B, which are known to contain tandem repeats of variable length, are examined. The results are shown in the following table. The numbers indicate the number of copies of the tandem repeat in a particular allele; e.g. male 1 has one allele with 8 and another allele with 9 copies of the tandem repeat in locus A. Which man, if any, could have been the alleged father of child 1? Motivate your answer.
Male 1 Male 2 Male 3 Woman Child 1 Child 2 Locus

Male 1 Male 2 Male 3 Woman Child 1 Child 2 Locus A 8/9 7/10 6/8 8/8 7/8 8/8 Locus B 5/7 7/7 5/5 3/5 5/7 3/7

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