1. As fluorine-18 decays, what isotope does it form? a) Fluorine-19.

b) Oxygen-18.

c) Boron-11.

2. Iodine-123, Iodine-124, and Iodine-125 are radioisotopes of the element iodine which has an atomic number (Z) of 53. How many neutrons are there in iodine-124? a) 71

b) 70

c) 72

3. Using the Decay Calculator tool, determine the answer to the following question: A vial containing a gallium-68 radiopharmaceutical has 500 MBq at 09:00 on 21st July 2014. How much will this vial contain at 10:00 on 21st July 2014? a) 495.59

b) 270.53

c) 500

4. How does iodine-123 decay? a) By electron capture.

b) By isomeric transformation.

c) By alpha decay.

5. Which of the following is a SPECT radioisotope? a) Indium-111.

b) Fluorine-18.

c) Carbon-11.

6. The SPECT radiopharmaceuticals [99mTc]sodium pertechnetate and [123I]sodium iodide are used to image the: a) heart.

b) brain.

c) thyroid

7. PET/CT with [18F]FDG may be used to diagnose cancer. The combination of PET with CT (PET/CT) is advantageous over PET alone because:

a) With PET/CT, CT provides metabolic information that PET does not provide.

b) PET/CT offers improved diagnostic accuracy and localisation of tumours over PET.

c) CT doesn't add any benefit when combined with PET in the diagnosis of cancer using [18F]FDG.

8. Which of the following PET radiopharmaceuticals is used for the study of glucose metabolism?

a) [18F]FDG.

b) [18F]NaF.

c) [11C]PIB.

9. Microbial testing is performed to ensure the radiopharmaceutical is:

a) stable.

b) chemically pure.

c) sterile and pyrogen free.

10. Quality control tests fall into two categories, physiochemical tests and microbiological tests. Which of the following tests is a microbiological NOT a physiochemical test method:

a) Limulus Amebocyte Lysate (LAL).

b) Gas Chromatography (GC).

c) Gamma Spectroscopy.