Question: 1. Consider a weak acid (pKa=8) dissolved in an aqueous solution with pH= 6. What is the ratio between the conjugate base A- and the
1. Consider a weak acid (pKa=8) dissolved in an aqueous solution with pH= 6. What is the ratio between the conjugate base A- and the acid form HA of this compund in the solution?
2. Acetyisalicylic acid (aspirin) is an acid with a pKa-4. We normally take aspirin orally, in tablet form. Assume that aspirin from a tablet enters the small intestine (pH= 7). Will it be in acid form (HA) and neutral, or will it lose its proton and become negatively charged acetylsalicylate (A-)? Justify your answer.
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