1. If the cell isn't making ATP through oxidative phosphorylation, what mechanism is being used to make ATP? Thinking about the pathways that make up Cellular Respiration, which ones can use mechanisms other than oxidative phosphorylation to make ATP? 12.?

2. Looking at the chart from Tainer's research, why were patients losing weight???

3. Look at Table 2. This is supposed to show the relationship between dosage and weight loss per week. If you just look at the first and last columns, what would you conclude? Look at the other columns - do any of the data in these columns give you reason(s) to doubt your conclusions??

4. ?Look at Table 3. Does the effectiveness of DNP depend on previous diet treatments? Can you tell from these data if DNP is better than the treatments listed??

5.Looking at this chart, should we, or our government be concerned about the availability of DNP online??

METABOLISM 22 30 CONTROL PERGO 80 Fot of -0 210 I 200 130 13100L 10 O DINITROPHENOL 3MG/KG PER DAY ORALLY 10 20 30 40 DAYS 50 60 70 80 with PERIDO Chart 2.-Effects of repeated daily oral doses of dinitrophenol on basa! metabolic rate and body weight, and return of metabolism to normal after administration has been stopped. TABLE 2.-Ratio Between Dosage and Rate of Loss of Body Weight Dose, Gm. 0.1 0.2 0.3 0.35 0.4 0.5 0.6 0.7 0.8 Number of Patients 37 145 154 10 Previous Treatment 95 34 10 1 ****** No diet or thyrold Only thyroid.. Only diet.... Diet ***** and thyroid together....... Total Number of Days ***** 516 3,503 4,718 739 3,765 1,417 472 16 Number of Cases 99 17 26 28 Average Number of Days per Patient HATTAATST 14 0.32 0.33 0.35 0.33 24 31 74 40 42 16 TABLE 3.-Influence of Previous Type of Treatment on the Rate of Response to Dinitrophenol 7 Total Weight Loss, Pounds 69 637 894 166 697 237 149 7 3 Average Weight Loss, Pounds per Patlent Weekly Average Average Dally Dose of Duration of Dinitrophenol, Dinitrophenol, Gm. Days 82 89 91 111 0.94 1.28 1.33 1.59 1.30 1.17 2.21 3.08 3.00 Average Loss, Pounds per Week 1.45 1.47 1.55 1.02