Question: 1) To model which indicator, studies are conducted on a monolayer of Caco-2 cell culture? 2) Define the terms pharmacokinetic phase and pharmacodynamic phase in

1) To model which indicator, studies are conducted on a monolayer of Caco-2 cell culture?

2) Define the terms pharmacokinetic phase and pharmacodynamic phase in the context of drug action. List the main factors influencing these phases. What are the different areas of drug metabolism in the body? Why is the liver considered the main "place" for metabolism?

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