1. Two groups of people with coronary heart disease receive two different drugs. The patients are followed...
Question:
1. Two groups of people with coronary heart disease receive two different drugs. The patients are
followed over time. Among the patients in the first group, 1.7% eventually suffered a heart
attack. 0.9% of the patients in the second group eventually suffered a heart attack.
(a) Does this imply that the second drug works significantly better?
(b) If I provide you the additional information that both groups had 500 patients, how will your
answer change?
2. Assuming that the population proportions are same as the sample proportions obtained in #1
above, what is the sample size that you actually need to detect that difference across the two
groups? Let's use an 80% power when calculating the sample size.
You must explain what test you are using, the hypotheses you are testing, and the values you
are using as input in the sample size calculator.
Statistics for the Life Sciences
ISBN: 978-0321989581
5th edition
Authors: Myra Samuels, Jeffrey Witmer, Andrew Schaffner