Question: 14.6 Let H, be a random variable denoting the handedness of an individual z, with possible values I or r. A common hypothesis is that

14.6 Let H, be a random variable denoting the
14.6 Let H, be a random variable denoting the handedness of an individual z, with possible values I or r. A common hypothesis is that left- or right-handedness is inherited by a simple mechanism; that is, perhaps there is a gene Gr, also with values / or r, and perhaps actual handedness turns out mostly the same (with some probability s) as the gene an individual possesses. Furthermore, perhaps the gene itself is equally likely to be inherited from either of an individual's parents, with a small nonzero probability m of a random mutation flipping the handedness. a. Which of the three networks in Figure 14.20 claim that P(Gfather, Gmother, Gchild) = P(Gfather ) P(G mother ) P(G child )? b. Which of the three networks make independence claims that are consistent with the hypothesis about the inheritance of handedness? mother Gamer G mother Gather Heather Gchild Hedid Hewild (a) (b) (c) Figure 14.20 Three possible structures for a Bayesian network describing genetic inheri- tance of handedness. c. Which of the three networks is the best description of the hypothesis? d. Write down the CPT for the Gemain node in network (a). in terms of s and m. e. Suppose that P(Gfather =1) = P(Gmother =1) = q. In network (a), derive an expres- sion for P(Gehaz = 1) in terms of m and q only, by conditioning on its parent nodes. f. Under conditions of genetic equilibrium, we expect the distribution of genes to be the same across generations. Use this to calculate the value of q, and, given what you know about handedness in humans, explain why the hypothesis described at the beginning of this question must be wrong

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