Question: ( 2 5 pts ) To evaluate the statistical significance of certain properties in DNA sequences, We need to generate many random shuffled DNA sequence

(25 pts) To evaluate the statistical significance of certain properties in DNA sequences, We need to generate many random shuffled DNA sequence instances from one or more given DNA sequences. A simple swapping-based algorithm can generate random sequences preserving the same nucleotide frequencies as the input sequences. In some applications, however, it is also expected to preserve the same k -mer
( 2 5 pts ) To evaluate the statistical

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