Question: 2 6 . 6 Consider the drug patch shown in Problem 2 6 . 4 . The patch consists of a pure solid drug source
Consider the drug patch shown in Problem The
patch consists of a pure solid drug source mounted on top of a
waterswollen polymer, which acts as a controlled diffusion
barrier. The square patch is cm cm The bottom
surface of the diffusion barrier is in direct contact with the skin.
The desired amount of cumulative drug release is mu mole
after hours. Independent experiments have shown that the
drug is immediately taken up into the body after exiting the
patch. The maximum solubility of the drug in the waterswollen
polymer is mu molecm
which is dilute. The effective
diffusion coefficient DAe of the drug in the waterswollen
polymer is cms What is the required thickness
L of the diffusion barrier component of the drug patch needed
to achieve the desired drug release profile?
Step by Step Solution
There are 3 Steps involved in it
1 Expert Approved Answer
Step: 1 Unlock
Question Has Been Solved by an Expert!
Get step-by-step solutions from verified subject matter experts
Step: 2 Unlock
Step: 3 Unlock
