3. First, define the following terms:

1. Sensitivity
2. Specificity
3. Positive predictive value
4. Negative predictive value

For the screening test for Down Syndrome the following results were obtained:

Screening Test Result	Affected Fetus	Unaffected Fetus	Total
Positive	10	300	310
Negative	2	4,442	4,444
Total	12	4,742	4,754

Based on the data above, calculate the following:

1. Sensitivity
2. Specificity
3. Positive predictive value
4. Negative predictive value

Please interpret your results. What do these results tell you about Down Syndrome in this population? Could any conclusions be drawn from this data?