5. Hydrochlorothiazide is shown below, along with a potential development candidate. hydrochlorothiazide development candidate a. Identify the functional groups present in hydrochloristhiazide, and indicate whether they are acidic, basic or neutral. (2 marks) b. Compare and contrast the structures of noradrenaline, propranolol and atenolol Noradrenaline propranolol atenolol Within your answer describe: i. How antagonist activity at beta receptors is achieved in propranolol and atenolol, while maintaining affinity. (2 marks) ii. How increasing selectivity for specific adrenergic receptors is achieved within this sequence. (2 marks) iii. How undesirable CNS effects are reduced when comparing propranolol and atenolol. (1 mark)