$6$

Multiple Choice

$5$ points

Please select the correct statement $($five points$)$:

Mouse monoclonal antibodies are not antigenic in humans. A mouse monoclonal antibody can be used for in vivo treatment of patients with cancer many times without concerns of inducing an anti$-$mouse antibody, because of the high homology of mouse and human immunoglobulins.

Although many monoclonal antibodies are specific for single antigenic epitopes, a large number of monoclonal antibodies recognize multiple antigenic epitopes.

A human$-$murine chimeric monoclonal antibody is$,$ in general, an antibody constructed by fusing the antigen binding region, VH and VL$,$ from a mouse antibody with the constant domain, Fc region, from human immunoglobulin.