7. Suppose a mutation changes a codon in a gene from GTA (or GUA in mRNA)...
Fantastic news! We've Found the answer you've been seeking!
Question:
Transcribed Image Text:
7. Suppose a mutation changes a codon in a gene from GTA (or GUA in mRNA) to GAA. What is the corresponding amino-acid change? What are two ways in which this small change in DNA could produce a drastic change in the function of the protein encoded by this gene? 8. Suppose a gene's coding region begins with the sequence ATGCTCCGGCAAAGG. A gene in another organism begins with the sequence ATGTTAAGAAACCGT, so there does not seem to be much sequence similarity. Is it likely that these two genes encode proteins of similar functions? (Hint: Translate the sequences before answering the question.) 9. Examine the BLOSUM62 substitution matrix and list 3 amino acid pairs that are more likely to replace each other in a protein sequence with a positive score. Give examples of amino acids that are the least likely to be replaced by another amino acid in a protein? 7. Suppose a mutation changes a codon in a gene from GTA (or GUA in mRNA) to GAA. What is the corresponding amino-acid change? What are two ways in which this small change in DNA could produce a drastic change in the function of the protein encoded by this gene? 8. Suppose a gene's coding region begins with the sequence ATGCTCCGGCAAAGG. A gene in another organism begins with the sequence ATGTTAAGAAACCGT, so there does not seem to be much sequence similarity. Is it likely that these two genes encode proteins of similar functions? (Hint: Translate the sequences before answering the question.) 9. Examine the BLOSUM62 substitution matrix and list 3 amino acid pairs that are more likely to replace each other in a protein sequence with a positive score. Give examples of amino acids that are the least likely to be replaced by another amino acid in a protein?
Expert Answer:
Answer rating: 100% (QA)
GUA codes for Valine and GAA codes for glutamic acid So the mutation changes the corresponding amino ... View the full answer
Related Book For
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
Posted Date:
Students also viewed these programming questions
-
What are some techniques Company can employ to measure consumer satisfaction and loyalty, and how can they use this data to improve their products and services?
-
Proteins are synthesized with a particular amino acid sequence through the translation of information encoded in messenger RNA by an RNAprotein complex called a ribosome. Amino acids are specified by...
-
Name 2 advantages of using IPv6 compared with using IPv4. 2) When an IPv6 device with no pre-configured IPv6 address powers up, it can calculate a global 128- bit IPv6 address for itself using...
-
4. (8 points) Fill in with =, >, >=,
-
Determine the location (xc, yc) of the center of gravity of the homogeneous wire bent in the form of a triangle. Neglect any slight bends at the corners. If the wire is suspended using a thread T...
-
What is the benefit of dividing an asset-backed security into tranches?
-
You have collected the following data: If you place these five numbers in a bag and randomly select one, what is the probability the number (X) will be ... a. equal to 6 ? b. less than 11 ? c....
-
In 2013, Aquaculture Incorporated applied for several commercial fishing licences for its commercial fishing vessels. The application was successful and on January 2, 2014, Aquaculture was granted 22...
-
On June 3 0 , Indigo Corporation discontinued its operations in Mexico. During the year, the operating income was $ 2 1 0 , 0 0 0 before taxes. On September 1 , Indigo disposed of the Mexico facility...
-
Case Introduction Established in 1967, Denns Fish House is a regional restaurant headquartered in a Southern US City, with dine-in buffet restaurants and several fast-food franchise locations....
-
Electricity is sold for $.12 per kilowatt-hour for the first 10000 units each month and $.09/kWh for all remaining units. if a firm uses 14000 kWh/month, what is its average and marginal cost?...
-
Parameter and Statistic What is a parameter, and what is a statistic?
-
Distracted Driving In a AAA Foundation for Traffic Safety survey, 21% of the respondents said that they recently texted or e-mailed while driving. Determine whether the given value is a statistic or...
-
Which do you think has less variation: the IQ scores of students in your statistics class or the IQ scores of a simple random sample taken from the general population? Why?
-
Carbon monoxide is measured in San Francisco on five different days, and the mean of those five values is 0.62 parts per million. Four of the values (in parts per million) are 0.3, 0.4, 1.1, and 0.7....
-
HDTV Penetration In a random sample of households, it was found that 47% of the sampled households had high-definition TVs. Determine whether the given value is a statistic or a parameter.
-
Electric charge is uniformly distributed inside a nonconductingsphere of radius 0.30m. the electric field at a point p, which is0.50m from the center of the sphere, is 17,000 N/C and is...
-
On October 1, 2021, Adoll Company acquired 2,600 shares of its $1 par value stock for $38 per share and held these shares in treasury. On March 1, 2023, Adoll resold all the treasury shares for $34...
-
An Analyze the Data question for this chapter can be found at the Molecular Cell Biology website: www.whfreeman.com/lodish7e
-
Movement of glucose from one side to the other side of the intestinal epithelium is a major example of transcellular transport. How does the Na + /K + ATPase power the process? Why are tight...
-
Describe how complementation analysis can be used to reveal whether two mutations are in the same or in different genes. Explain why complementation analysis will not work with dominant mutations?
-
The number on the jersey of each New York Giants football player is recorded, then the mean of those numbers is computed. Decide whether the statement makes sense (or is clearly true) or does not...
-
A professor calculates final grades using a weighted mean in which the final exam counts twice as much as the midterm. Decide whether the statement makes sense (or is clearly true) or does not make...
-
The following ages (years) of survey respondents: 22, 19, 21, 27, over 65, over 80. State whether the mean or median would give a better description of the average. Explain your reasoning.
Study smarter with the SolutionInn App