a) Apply Lipinskis Rules to the structure of lamivudine. (4 marks) b) What does your Lipinski analysis
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Question:
a) Apply Lipinski’s Rules to the structure of lamivudine. (4 marks)
b) What does your Lipinski analysis tell you about the suitability of lamivudine as a drug? What are the limitations of this analysis? (2 marks)
c) By comparing the structure of lamivudine 1 to cytosine deoxyribonucleotide 2, explain briefly how this drug might inhibit reverse transcriptase, and how doing so can fight HIV/ AIDS. (2 marks)
Related Book For
Organic Chemistry A Short Course
ISBN: 978-1111425562
13th edition
Authors: Harold Hart, Christopher M. Hadad, Leslie E. Craine, David J. Hart
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