Question: A clinical trial was conducted comparing a new compound designed to improve wound healing in trauma patients to a placebo. After treatment for 5 days,

  1. A clinical trial was conducted comparing a new compound designed to improve wound healing in trauma patients to a placebo. After treatment for 5 days, 58% of the patients taking the new compound had a substantial reduction in the size of their wound as compared to 44% in the placebo group. The trial failed to show significance. How many subjects would be required to detect the difference in proportions observed in the trial with 80% power? A two sided test is planned at a=0.05.

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