A Friedel-Crafts acylation of anisole with acetyl chloride affords a binary product with a total mass...

 

  

Transcribed Image Text:

A Friedel-Crafts acylation of anisole with acetyl chloride affords a binary product with a total mass of 1.91 grams. This product is analyzed by gas chromatograph. The chromatogram shows two product peaks identified as ortho-methoxy acetophenone and para-methoxy acetophenone. Answer the following questions. H3CO Anisole MW: 108.14 H3C Acetyl chloride MW: 78.50 AICI3, THF 0 °C to rt, 4 h H3C H3CO + ortho-methoxy acetophenone MW: 150.17 GC uncorrected area = 12 mm² Response factor = 1.08 H₂CO CH3 Para-methoxy acetophenone MW: 150.17 GC uncorrected area = 134 mm² Response factor = 1.02 A) Using all the data given above calculate the molar percent compositions of each of the two isomeric products obtained in the reaction. Also, calculate the mass of each of the two isomeric products in grams. Show all work. B) A student conducted the above reaction with 2.64 g of anisole and 2.36 g of acetyl chloride. He purified the product mixture by column chromatography and obtained 0.1254 g of ortho-methoxy acetophenone and 1.6843 g of para- methoxy acetophenone. Show how you would find out the limiting reagent. Show how you would calculate the number of moles of the materials needed. Calculate the theoretical yield and percent yield for each of the isomeric products. Show all calculations and write down all appropriate formulas. A Friedel-Crafts acylation of anisole with acetyl chloride affords a binary product with a total mass of 1.91 grams. This product is analyzed by gas chromatograph. The chromatogram shows two product peaks identified as ortho-methoxy acetophenone and para-methoxy acetophenone. Answer the following questions. H3CO Anisole MW: 108.14 H3C Acetyl chloride MW: 78.50 AICI3, THF 0 °C to rt, 4 h H3C H3CO + ortho-methoxy acetophenone MW: 150.17 GC uncorrected area = 12 mm² Response factor = 1.08 H₂CO CH3 Para-methoxy acetophenone MW: 150.17 GC uncorrected area = 134 mm² Response factor = 1.02 A) Using all the data given above calculate the molar percent compositions of each of the two isomeric products obtained in the reaction. Also, calculate the mass of each of the two isomeric products in grams. Show all work. B) A student conducted the above reaction with 2.64 g of anisole and 2.36 g of acetyl chloride. He purified the product mixture by column chromatography and obtained 0.1254 g of ortho-methoxy acetophenone and 1.6843 g of para- methoxy acetophenone. Show how you would find out the limiting reagent. Show how you would calculate the number of moles of the materials needed. Calculate the theoretical yield and percent yield for each of the isomeric products. Show all calculations and write down all appropriate formulas.

Answer rating: 100% (QA)

2 A Given total mass or the product area 12 mm Para pordnet area a 134 ... View the full answer