Question: A frog mutant was found in which oocytes developed normally at 3 0 oC following fertilization, but did not develop at all at 3 7

A frog mutant was found in which oocytes developed normally at 30oC following fertilization, but did not develop at all at 37oC. Examination of RNA in the fertilized oocyte at 37oC showed the absence of polyadenylated mRNA A. Mutations in which of the following elements in the oocyte could account for these observations? You may choose one or more answers. Write a brief explanation for your choice(s).(a) eIF4E (the CAP-binding protein)(b) An amber mutation in the gene coding for Maskin protein (c) The UUUUAU sequence (CPE) in an essential mRNA (d) The CPE-binding protein (CPEB)(e) eIF4G (the "scaffolding protein" that binds the CAP-binding protein)(f) The AAUAAA sequence (poly(A) addition signal) in an essential mRNA (g) The cytoplasmic poly(A) polymerase (PAP)(h) PABP1(cytoplasmic poly(A) binding protein 1)(i) none of the above

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