Question: A frog mutant was found in which oocytes developed normally at 3 0 oC following fertilization, but did not develop at all at 3 7
A frog mutant was found in which oocytes developed normally at oC following fertilization, but did not develop at all at oC Examination of RNA in the fertilized oocyte at oC showed the absence of polyadenylated mRNA A Mutations in which of the following elements in the oocyte could account for these observations? You may choose one or more answers. Write a brief explanation for your choicesa eIFE the CAPbinding proteinb An amber mutation in the gene coding for Maskin protein c The UUUUAU sequence CPE in an essential mRNA d The CPEbinding protein CPEBe eIFG the "scaffolding protein" that binds the CAPbinding proteinf The AAUAAA sequence polyA addition signal in an essential mRNA g The cytoplasmic polyA polymerase PAPh PABPcytoplasmic polyA binding protein i none of the above
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