Question: A new rapid diagnostic test was evaluated for its ability to detect Zika, providing a result in 20 minutes. A study aims to determine whether

A new rapid diagnostic test was evaluated for its ability to detect Zika, providing a result in 20 minutes. A study aims to determine whether the rapid test is an effective tool in detecting the Zika virus compared to the gold standard method (the plaque reduction neutralization test, PRNT for short) for the confirmation of the presence of anti-Zika antibodies. The results of the investigation are tabulated below.

PRNT

Zika +

PRNT

Zika -

Total

Rapid test +

86

89

175

Rapid Test -

14

12,311

12,325

Total

100

12,400

12,500

Compute and interpret a 95% confidence interval for the sensitivity of the rapid test.

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