A process or system for updating needs to be established. This system should specify

the frequency for reviewing the manual, assign responsibility for updating to

someone $($usually the quality manager$),$ and define how changes in the manual will

be incorporated and documented. Changes to the quality manual will need to be

approved; approval should be indicated by having signatures of the person$($s$)$ with

authority to make changes, and the date of the change, recorded in the manual.

$$ Instruction on use of the manual should be provided to all laboratory staff;

laboratory personnel must understand that the policies detailed in the quality manual

are always to be followed. list quiz MCQ questions with answers