Question: A transdermal patch is designed to deliver Methadone. Before the drug is delivered across the skin, it diffuses through a rate - controlling membrane between
A transdermal patch is designed to deliver Methadone. Before the drug is delivered across the skin, it diffuses through a ratecontrolling membrane between the drug reservoir and skin. The surface area, thickness, diffusion coefficient, and partition coefficient K OilWater of the membrane is cmmu m cm sec and respectively. Calculate the permeability coefficient of this drug through this membrane.
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