Question: a) Using Zimmerman-Traxler transitions state models, explain why the observed C(3)C(4) stereochemistry is formed in product (C). Is this the syn or anti isomer? (10

a) Using Zimmerman-Traxler transitions state models, explain why the observed C(3)–C(4) stereochemistry is formed in product (C). Is this the syn or anti isomer? (10 marks)

LDA OH THF -78 C Me Si Me Me Me O. (B)n

LDA OH THF -78 C Me Si Me Me Me O. (B) Me Me 'Bu "Bu Me (A) (C) recall that LDA = N.

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It is an enantioselective aldol condensation reaction LDA first reacts with silyloxy ketones to form ... View full answer

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