Activity I. Genetic Problems

Eric and Ariel contacted a genetic counselor just after their daughter Melody's first birthday. Melody had recently been diagnosed with cystic fibrosis $($CF$),$ an autosomal recessive $($Not X linked, No X or Y $)$ inherited disorder in which excessively thick mucus is produced, blocking ducts in the body and accumulating in the lungs. Neither parents know of anyone else in the family that has cystic fibrosis, but were concerned that their future children would also inherit the disease.

Normal Lung function $=F$

Cystic fibrosis $=f$

What are the genotypes for cystic fibrosis of$....$

Eric? $q,$ Ariel? $q,$ Melody? $q,$

What are the chances that Eric and Ariel's next child will have CF$?$ Please show your punnet square or explain.

A$.0\%$

B$.25\%$

C$.50\%$

D$.66\%$

E$.75\%$

F$.100\%$

Fill in the columns in the table below by identifying the surface antigens and antibodies present in the plasma for the ABO blood types given. For the final two columns, think about the antigens and antibodies present for each ABO blood type, and the reactions that would occur with introduction of each of the other ABO blood types.

$\backslash$table$[[$Blood Type,$\backslash$table$[[$Surface Antigens$],[$Present$]],\backslash$table$[[$Antibodies$],[$in Plasma$]],\backslash$table$[[$Can safely$],[$donate to types:$]],\backslash$table$[[$Can safely receive$],[$blood from types:$]]],[A,,$Anti$-$B$,,A,O$