Question: An infant develops vomiting and lethargy several days after birth. The mother also notices an unusual, sweet odor like burnt sugar in her diapers. Blood

 An infant develops vomiting and lethargy several days after birth. The
mother also notices an unusual, sweet odor like burnt sugar in her
diapers. Blood chemistry reveals metabolic acidosis due to ketoacidosis. A diagnosis of

An infant develops vomiting and lethargy several days after birth. The mother also notices an unusual, sweet odor like burnt sugar in her diapers. Blood chemistry reveals metabolic acidosis due to ketoacidosis. A diagnosis of maple syrup urine disease is made. This disorder is due to a deficiency in the branched-chain ketoacid dehydrogenase enzyme, which metabolizes amino acid with branched, hydrophobic side chains. Which of the following amino acids should be restricted from this infant's diet? Answers A-E A Cysteine, methionine, glutamate B Lysine, arginine, glutamine C Proline, glycine, aspartate D Tyrosine, phenylalanine, histidine E Leucine, valine, isoleucine Quinine is now contraindicated as a long-term prophylactic against malaria because of its association with the development of blackwater fever, an adverse reaction resulting in hemolysis. The hemolysis is produced when quinine binds to proteins in the surface of red blood cells (RBC), together creating an immunogen against which the hemolytic antibodies are formed and therefore an immune response is directed. Which of the following is the most likely role of quinine in the development of this hemolytic anemia? Answers A - E A An immunogen B An antigen binding fragment A hapten D An autoantigen E A carrier 24-year-old woman develops tearing of the eyes, sneezing, and coughing 3 hours after. visiting a friend with a cat. Which of the following is true about the immunoglobulin molecule related to the development of these symptoms? Answers A-E A Its heavy chain contains 4 constant domains B Has both monomeric and dimeric forms C It has a pentameric structure D Can cross the placenta E Can contain J chains

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