[ Answer Questions based on Relevant Research Articles.] Table 2 below is a summary report from a clinical research. The research objective is to assess the risk of off-label use of atypical antipsychotics in patients with bipolar disorder. Please answer following two questions:

Psychiatry specialist prescribers

Substance abuse disorder

Hypertension

Bipolar disorder

Diabetes mellitus

Table 2 Off-Label Use Odds Ratio for Patients with Bipolar Disorder, 1998-2002 Patients Patients w/>2 Rx (n = 105,771) (n = 58,918) Odds ratio (95% Odds ratio (95% Variables confidence interval) confidence interval) Sex (male = 1) 0.78 (0.77-0.83) 0.82 (0.78 0.87) Age 1.001 (0.99.1.01) 0.998 (0.99-1.00) Psychiatric specialist 1.52 (1.44-1.59) 1.57 (1.49-1.66) Key psychiatric comorbidities Alcohol abuse 1.01 (0.93-1.11) 1.03 (0.93-1.14) Substance abuse 1.51 (1.37-1.66) 1.44 (1.30-1.60) Anxiety disorder 1.20 (1.14-1.26) 1.08 (1.03-1.14) Impulse-control disorder 1.17 (0.97-1.42) 1.14 (0.93-1.40) Personality disorder 1.47 (1.33-1.63) 1.64 (1.47-1.83) Eating disorder 1.18 (0.97-1.43) 1.11 (0.90-1.37) General medical comorbidities Diabetes mellitus 1.26 (1.16-1.37) 1.24 (1.14-1.35) Cancer 0.93 (0.73-1.18) 0.91 (0.71-1.18) Hypertension 1.12 (1.05-1.20) 1.10 (1.03-1.18) Chronic obstructive 1.07 (0.95-1.21) pulmonary disease 1.12 (0.99-1.27) Cerebrovascular disease 1.27 (1.12-1.44) 1.26 (1.10-1.45) Ischemic heart disease 0.95 (0.84-1.07) 0.94 (0.83-1.07) Arthritis 1.07 (0.93-1.23) 0.98 (0.85-1.14) Obesity 1.19 (1.09.1.30) 1.27 (1.15-1.39) Model goodness-of-fit Chi-square = 766.73 Chi-square = 639.76 -2 Log likelihood = -2 Log likelihood = 53,379, P <.001 p table off-label use odds ratio for patients with bipolar disorder w>2 Rx (n = 105,771) (n = 58,918) Odds ratio (95% Odds ratio (95% Variables confidence interval) confidence interval) Sex (male = 1) 0.78 (0.77-0.83) 0.82 (0.78 0.87) Age 1.001 (0.99.1.01) 0.998 (0.99-1.00) Psychiatric specialist 1.52 (1.44-1.59) 1.57 (1.49-1.66) Key psychiatric comorbidities Alcohol abuse 1.01 (0.93-1.11) 1.03 (0.93-1.14) Substance abuse 1.51 (1.37-1.66) 1.44 (1.30-1.60) Anxiety disorder 1.20 (1.14-1.26) 1.08 (1.03-1.14) Impulse-control disorder 1.17 (0.97-1.42) 1.14 (0.93-1.40) Personality disorder 1.47 (1.33-1.63) 1.64 (1.47-1.83) Eating disorder 1.18 (0.97-1.43) 1.11 (0.90-1.37) General medical comorbidities Diabetes mellitus 1.26 (1.16-1.37) 1.24 (1.14-1.35) Cancer 0.93 (0.73-1.18) 0.91 (0.71-1.18) Hypertension 1.12 (1.05-1.20) 1.10 (1.03-1.18) Chronic obstructive 1.07 (0.95-1.21) pulmonary disease 1.12 (0.99-1.27) Cerebrovascular disease 1.27 (1.12-1.44) 1.26 (1.10-1.45) Ischemic heart disease 0.95 (0.84-1.07) 0.94 (0.83-1.07) Arthritis 1.07 (0.93-1.23) 0.98 (0.85-1.14) Obesity 1.19 (1.09.1.30) 1.27 (1.15-1.39) Model goodness-of-fit Chi-square = 766.73 Chi-square = 639.76 -2 Log likelihood = -2 Log likelihood = 53,379, P <.001 p>