Question: answer step by step please Question 6: Chromatography (4 Marks) Lets say a drug molecule is chromatographed on two different liquid chromatography columns under different

answer step by step please

Question 6: Chromatography (4 Marks) Lets say a drug molecule is chromatographed on two different liquid chromatography columns under different conditions and the following data collected (a) Calculate the number of theoretical plates on both columns (assume Gaussian peak shapes are obtained) (1 Mark) (b) Calculate the HETP (in cm/ plate) for both columns. (1 Mark) (c) Which column is better in terms of HETP? (1 Mark) (d) What is the HETP for conditions under which the drug molecule elutes at tr=3.715min, W1/2=0.083min, with a 15cm column. (1 Mark) Question 6: Chromatography (4 Marks) Lets say a drug molecule is chromatographed on two different liquid chromatography columns under different conditions and the following data collected (a) Calculate the number of theoretical plates on both columns (assume Gaussian peak shapes are obtained) (1 Mark) (b) Calculate the HETP (in cm/ plate) for both columns. (1 Mark) (c) Which column is better in terms of HETP? (1 Mark) (d) What is the HETP for conditions under which the drug molecule elutes at tr=3.715min, W1/2=0.083min, with a 15cm column. (1 Mark)

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock blur-text-image

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related Chemical Engineering Questions!

Nucleon 1) Describe the vertical chain for biotechnology productions. What "make" decisions has Nucleon already made? What "buy" decisions has it already made? Evaluate these decisions. 2) Draw a...

chegg.com/homework-help/questions-and-answers/1-describe-vertical-chain-biotechnology-productions-make The CRP-1 Project: Current Applications Since Nucleon's founding, its main development project...

only numbers 3,4 and 5 thank you TAXES! When it comes to how the American household is taxed, every family is different. We will start with a model suggesting that the average U.S. household earns a...

Study Guide Healthcare Statistics By Jacqueline K. Wilson, RHIA About the Author Jacqueline K. Wilson is a Registered Health Information Administrator (RHIA) who has more than ten years of experience...

ID Salary 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 65.1 27 36.1 61.4 46.6 73.3 39.7 23.2 74.6 22.8 23.4 62 40.7 23 24 51.1...

The best definition for nonparametric statistics I can think of is when data does not fit inside the normal parameters of a normal distribution, it calls for the use of this statistical method....

413-432_CH18_Nachmias.qxd 1/17/07 3:47 PM Page 413 Chapter Index Construction and Scaling Methods INDEX CONSTRUCTION The Purpose of the Index The Sources of the Data The Base of Comparison Methods of...

Overview Nineteen67apparel is an apparel e-commerce company in London Ontario. This town is heavily populated with university students and young professionals, the total population of university...

Please answer the following questions after reading Lectures 3,4 and 5: 1. Please list, describe and explain each one of the five major types of taxes as discussed in Lectures 3,4, and 5: What is the...

ADMN 233 Assignment 4 Assignment 4 Instructions Assignment 4 is worth 20% of your final mark. It should be completed and submitted after you finish Chapter 13 in your textbook. This assignment is...

In what situations do you believe that strategy formulation leads to strategy implementation? In what situations do you believe that strategy implementation plays an equal role with strategy...

Is accrual accounting more closely related to a companys goal of profitability or liquidity?

There are two projects. One has an IRR of 1 4 , and an NPV 0 f 1 0 0 0 0 while the other has an IRR of 1 2 and an NPV of 8 0 0 0 . Which project do you choose and why? Of NPV and IRR why is the...

The use case model with potential actors and use cases. Appropriate use of the structuring options of UML use case diagram ( e . g . , include, extend, and generalization / specialization ) . A short...

We have up to date physical safeguards, such as secure areas in buildings, electronic safeguards, such as passwords and encryption, and we have procedural safeguards, such as customer authentication...

A pitfall of internal promotions is, that a person may be given a job beyond their competence.

What makes this development possible is the technological advances in todays workplace.