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Which factor would lead to the development of an autoimmune response or hypersensitivity disease? C) Loss of ability of the immune system to initiate an immune response C) Reduction in the number of immune response cells C) Loss of ability of the adaptive immune system to distinguish between self and non-self-antigens Loss of ability of the immune system to distinguish between extracellular non-self-antigens and intracellular non-self-antigens