Question: (b) (PSS/PDADMAC)4 multilayers were loaded with the anticancer drug cisplatin at 22C. 10g of the drug, was loaded into multilayers assembled on a round silica

(b) (PSS/PDADMAC)4 multilayers were loaded with the anticancer drug cisplatin at 22C. 10g of the drug, was loaded into multilayers assembled on a round silica glass disk with diameter of 20mm. Calculate the concentration of the cisplatin inside the multilayers. The thickness of the (PSS/PDADMAC) 4 film prepared at 45C is 5.0107m. Relative molecular mass of the drug is 301gmol1. (7 marks) (c) Molecules of cisplatin diffuse into the (PDADMAC/PSS) 6 multilayers and the diffusion coefficient was found to be 0.41012m2s1 at 37C. How many hours would be required for the drug molecules to pass across the film? The thickness of the multilayers assembled on a 1cm sized square metal plate coated with a glass layer is 0.5m. (7 marks) (d) i) What is the ratio of the Debye length for a charged group on the backbone of PDADMAC in 1 and 2MNaCl water solution at 25C and pH7.8
Step by Step Solution
There are 3 Steps involved in it
Get step-by-step solutions from verified subject matter experts
