bioinformatics

The first step in the BLAST algorithm is seeding. Given the threshold 12, find 3 neighborhood words of the protein 3-mer QIE using PAM250 given below. You are also required to find the alignment scores fo each of them against QIE. ANN 4 ON A Ala 2 R Arg -2 6 N Asn 0 0 2 D Aspo -1 2 4 C Cys -2 -4 -5 Q Gin 0 1 1 2 4 E Glu 0 1 3 -5 2 4 G Gly 1 -3 1 -3 -1 0 5 H His -1 2 1 -3 3 1 -2 6 Ille -1 -2 -2 -2 -2 -2 -2 -3 -2 5 L Leu -2 -3 -3 -4 -6 -2 -3 -2 2 6 K Lys -1 3 1 0 -5 1 0 -2 0-2 -3 5 M Met -1 0 -2 -3 -5 -1 -2 -3 -2 2 4 6 F Phe -4 -4 -6 -4 -5 -5 -5 -2 1 2 -5 0 9 P Pro 1 0 -1 -1 -3 0 -1 -1 0-2 -3 -1 -2 -5 6 S Ser 1 1 0 0 1 -1 -1 -3 0 -2 -3 1 3 T Thr 1 -1 0 0 -2 -1 0 0 -1 0 -2 0 -2 1 3 W Trp -6 2-4 -7 -8 -5 -7 -7 -3 -5 -2 -3 -4 0 -6 -2 -5 17 Y Tyr -3 -4 -2 0 -4 -4 -5 0-1 -1 -4 -2 7 -5 -3 -3 0 10 V Val 0 -2 -2 -2 -2 -2 -2 -1 -2 4 2 -2 2 -1 -1 0 -6 -2 4 Ala Arg Asn Asp Cys Gin Glu Gly His lle Leu Lys Met Phe Pro Ser Thr Trp Tyr Val R N D Q E HIL K M F P S T W Y V 0 The first step in the BLAST algorithm is seeding. Given the threshold 12, find 3 neighborhood words of the protein 3-mer QIE using PAM250 given below. You are also required to find the alignment scores fo each of them against QIE. ANN 4 ON A Ala 2 R Arg -2 6 N Asn 0 0 2 D Aspo -1 2 4 C Cys -2 -4 -5 Q Gin 0 1 1 2 4 E Glu 0 1 3 -5 2 4 G Gly 1 -3 1 -3 -1 0 5 H His -1 2 1 -3 3 1 -2 6 Ille -1 -2 -2 -2 -2 -2 -2 -3 -2 5 L Leu -2 -3 -3 -4 -6 -2 -3 -2 2 6 K Lys -1 3 1 0 -5 1 0 -2 0-2 -3 5 M Met -1 0 -2 -3 -5 -1 -2 -3 -2 2 4 6 F Phe -4 -4 -6 -4 -5 -5 -5 -2 1 2 -5 0 9 P Pro 1 0 -1 -1 -3 0 -1 -1 0-2 -3 -1 -2 -5 6 S Ser 1 1 0 0 1 -1 -1 -3 0 -2 -3 1 3 T Thr 1 -1 0 0 -2 -1 0 0 -1 0 -2 0 -2 1 3 W Trp -6 2-4 -7 -8 -5 -7 -7 -3 -5 -2 -3 -4 0 -6 -2 -5 17 Y Tyr -3 -4 -2 0 -4 -4 -5 0-1 -1 -4 -2 7 -5 -3 -3 0 10 V Val 0 -2 -2 -2 -2 -2 -2 -1 -2 4 2 -2 2 -1 -1 0 -6 -2 4 Ala Arg Asn Asp Cys Gin Glu Gly His lle Leu Lys Met Phe Pro Ser Thr Trp Tyr Val R N D Q E HIL K M F P S T W Y V 0