Bioprocess Engineering

Question: In a pilot-scale UF process, a nonfouling macromolecule is filtered under constant TMP. Use the osmotic-pressure model to predict the permeate flux. The relationship between the osmotic pressure in bar (A) and the concentration of the macromolecule at the membrane in kg m (Cw) can be taken as -3 log Ar = 0.25 + 0.100,35. Operational Data: TMP: 10 bar Pure-water flux at 10 bar TMP: 7.5 X 10-5 m s -1 Concentration at the membrane (Cw): 100 kg m Permeate Viscosity (u): 1X10-3 Pas - 3