Question: Broad scientists created the visual below. They grouped the sequences based on sets of shared identical mutations, or core mutations. Take your virus sequences and
Broad scientists created the visual below. They grouped the sequences based on sets of shared identical mutations, or core mutations. Take your virus sequences and group them as illustrated in Figure 1. Figure 1. Groups of Ebola virus sequences. The sequences in each group have a set of shared core mutations. Within each group, some viruses may have additional mutations that are not shared by other viruses in the group. In your Word Document add a Section: Section: Ebola Sequence Analysis Using the grouping in Figure 1, list the core mutations that occurred between one group and the other. Core mutations are mutations shared by every virus in the group. Describe the mutation by indicating the nucleotide number in the sequence. Differences between the reference sample and the Group 1 sequences: Differences between groups 1 and 2 Differences between groups 2 and 3 What can you infer from this diagram about when each group of patients contracted Ebola relative to one another? Explain how the sequences and groupings support the hypothesis that mutations accumulate over time. How can you explain the fact that some sequences have additional (noncore) mutations that did not spread into other groups? If a particular mutation
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