Question: Can we work on this problem? What functions as (a) the GEF and (b) the GAP for a heterotrimeric GTPase ? PE Poll Q4 LO

Can we work on this problem?

What functions as (a) the GEF and (b) the GAP for a heterotrimeric GTPase ? PE Poll Q4 LO 2 GDP bound (inactive) Hormone E GTP Exterior GDP Inactive Trimeric Gs protein Inactive receptor Cytosol effector GAPS GEFs Ga RESTING Gy STATE GTP GDP ((1-))) GTP bound (active) A. The hormone is the GEF; the Go subunit is the GAP B. The GPCR is the GEF; the Go subunit is the GAP C. The hormone is the GEF; the effector is the GAP D. The GPCR is the GEF; the G, subunit complex is the GAP E. The GPCR is the GEF; the effector is the GAP D103 Cell Biology ALS 17 @ MacGregor, Suetterlin Wang - All rights reserved Page 5

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