Case study, please answer all questions

d. How is cach cell 3 Immune system and HIV a. Which type(s) of immune cells is/are targeted by HIV? b. Why are other cells not targeted by the virus? c. How should cytotoxic T cells respond to the initial phase of HIV infection (when some T helper cells are still functioning? Explain your reasoning, Page 3 "Resistance Is Futile... or Is It" by Annie Prud'homme-Gnreux NATIONAL CENTER FOR CASESTUDY TEACHING IN SCIENCE d. As time progresses, why do the cytotoxic T cells stop responding to the HIV infection Propose an explanation. c. What happens to the immune system after HIV infection? Why? Can this account for the symptoms of AIDS (.e., immunodeficiency, or the inability to defend against any foreign invaders like viruses and bacteria)? f Why do you suppose that there is a delay between the time of HIV infection and the appearance of symptoms (and AIDS)? g. How does HIV evade the immune system? 4. HIV protection a. Consider how HIV infects cells and reproduces. Also consider how the immune system fights off HIV infection. Humans differ by having mutations that result in slightly different proteins and immune function. Suggest as many hypotheses as possible to explain why some individuals might be protected against HIV infection. In other words, where and how might new viral infections be stopped? What could be different about the people who seem protected against HIV that caused viral replication to stop? Come up with at least three possibilities. EN