Chapter 11 - Mastery Part 1 X OWLv2 | Online teaching and le X Dashboard X + C prod01-cnow-owl.cengagenow.com/ilrn/takeAssignment/takeCovalentActivity.do?locator=assignment-take To * 0 0 Update : Chapter 23 - EOC [References] Question 1 1 pt N-Nitrosamines by themselves are not significant carcinogens. However, they are activated in the liver by a class of iron-containing enzymes (members of the ? Question 2 1 pt cytochrome P-450 family). Activation involves the oxidation of a C-H bond next to the amine nitrogen to a C-OH group. Question 3 1 pt O N NZO Question 4 pt OH Question 5 1 pt 02 H cyt P450 Question 6 pt Question 7 1 pt Question 8 O 1 pt The hydroxylation product can subsequently be transformed into an alkyl diazonium ion, an active alkylating agent and therefore a carcinogen, in the presence of an acid catalyst Question 9 1 pt Draw curved arrows to show the movement of electrons in this step of the reaction mechanism. Question 10 1 pt Arrow-pushing Instructions Question 11 1 pt nno- X T Question 12 1 pt Question 13 + 1 pt OH2 Question 14 1 pt N O N+ O HO Progress: 11/14 items Due May 10 at 08:00 AM Previous Next inish Assignment Email Instructor Save and Exit Cengage Learning | Cengage Technical SupportChapter 11 - Mastery Part 1 X OWLv2 | Online teaching and le X Dashboard X + C prod01-cnow-owl.cengagenow.com/ilrn/takeAssignment/takeCovalentActivity.do?locator=assignment-take Update : Chapter 23 - EOC [References] Question 1 1 pt 1. CH3CI, AICI3 ? Question 2 1 pt 2. HNO3. H2SO4 3. H2, Pd/C Question 3 1 pt 4. CH3COCI Question 4 1pt 5. HNO3, H2SO4 6. H3Ot, heat Question 5 ipt 7. NaNO2, HCI Question 6 pt 8. H3PO2 9. H2, Pd/C Question 7 1 pt 10. NaNO2, HCI 11. HBF4 Question 8 O 1 pt Question 9 1 pt Work through the synthesis on a separate sheet of paper, and then draw the structure(s) of the final organic product(s). Question 10 1 pt . You do not have to consider stereochemistry. Question 11 1 pt . Do not draw organic or inorganic by-products. . Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Question 12 1 pt Separate multiple products using the + sign from the drop-down menu. Question 13 1 pt Question 14 1 pt Progress: 11/14 items Due May 10 at 08:00 AM Previous inish Assignment Email Instruct Cengage Learning | Cengage Technical SupportChapter 11 - Mastery Part 1 X OWLv2 | Online teaching and le X Dashboard X + C prod01-cnow-owl.cengagenow.com/ilrn/takeAssignment/takeCovalentActivity.do?locator=assignment-take To * 0 0 Update : Chapter 23 - EOC [References] Question 1 1 pt This aromatic synthesis uses reaction of a diazonium salt as a key step. The transformation occurs in 5 steps and involves the following reactions: (1) nitration, (2) reduction, (3) acetylation, (4) Friedel-Crafts acylation, (5) hydrolysis. ? Question 2 1 pt Question 3 1 pt Question 4 1pt Question 5 1 pt H2N Question 6 pt Draw the structures of the products of reactions (2) and (3). Question 7 1 pt Question 8 O 1 pt . Do not draw organic or inorganic by-products. . Do not include counter-ions, e.g., Nat, I, in your answer. Question 9 1 pt . Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Question 10 Separate products from different steps using the - sign from the drop-down menu. 1 pt Question 11 1 pt Question 12 1 pt Question 13 1 pt Question 14 1 pt Progress: 11/14 items Due May 10 at 08:00 AM Previous Next ChemDoodle inish Assignment Email Instructor Save and Exit Cengage Learning | Cengage Technical Support