A 96 well plate assay is used to screen a library of compounds for inhibitors of...

Transcribed Image Text:

A 96 well plate assay is used to screen a library of compounds for inhibitors of biliverdin reductase, an enzyme that converts green biliverdin to yellow bilirubin. Enzyme activity is assessed through disappearance of the green colour. By mistake, one of the sample wells did not receive the enzyme. Assuming the library compound added to this well was actually not an inhibitor, which of the following statements is TRUE? The result from this sample well cannot be defined in one of these ways. This sample well will produce a false positive result. This sample well will produce a true negative result. This sample well will produce a false negative result. A 96 well plate assay is used to screen a library of compounds for inhibitors of biliverdin reductase, an enzyme that converts green biliverdin to yellow bilirubin. Enzyme activity is assessed through disappearance of the green colour. By mistake, one of the sample wells did not receive the enzyme. Assuming the library compound added to this well was actually not an inhibitor, which of the following statements is TRUE? The result from this sample well cannot be defined in one of these ways. This sample well will produce a false positive result. This sample well will produce a true negative result. This sample well will produce a false negative result.

Answer rating: 100% (QA)

This Sample well will produce false positive Result The upregulation of heme oxygenase1 HO1 has prov... View the full answer