Model 3: Retrosynthetic Analysis of the Aldol Condensation In retrosyntbeti analysis (refer to CA13), the product...
Fantastic news! We've Found the answer you've been seeking!
Question:
Transcribed Image Text:
Model 3: Retrosynthetic Analysis of the Aldol Condensation In retrosyntbetiç analysis (refer to CA13), the product is disconnected, or pulled apart, to determine the starting materials for the reaction. OH OH CH3 Ph CH3 + Ph ČH3 ČH3 E* Nu Product Synthons Questions: 6. Model 3 shows the partial retrosynthetic analysis of the aldol condensation. (a) Label the carbons of the product with Greek characters. At what position is the OH group? Is this product ah aldol condensation product? (Circle one) yes / no. In an aldol condensation, what position is the new bond formed between (refer to #1f)? On the product in Model 3, draw a line across the C-C bond that was formed to (b) make the aldol product. If the bond that was formed (marked in #6b) is disconnected or pulled apart, the synthons or (c) fragments, shown above are obtained. Complete these synthons by assigning a charge to the. fragment that acts as the EO and a O charge to the fragment that acts as the Nu O. (d) On an aldehyde, which carbon is the NuO and which is the EO? Check to make sure this agrees with the charges placed on the synthons in #4c. Model 3: Retrosynthetic Analysis of the Aldol Condensation In retrosyntbetiç analysis (refer to CA13), the product is disconnected, or pulled apart, to determine the starting materials for the reaction. OH OH CH3 Ph CH3 + Ph ČH3 ČH3 E* Nu Product Synthons Questions: 6. Model 3 shows the partial retrosynthetic analysis of the aldol condensation. (a) Label the carbons of the product with Greek characters. At what position is the OH group? Is this product ah aldol condensation product? (Circle one) yes / no. In an aldol condensation, what position is the new bond formed between (refer to #1f)? On the product in Model 3, draw a line across the C-C bond that was formed to (b) make the aldol product. If the bond that was formed (marked in #6b) is disconnected or pulled apart, the synthons or (c) fragments, shown above are obtained. Complete these synthons by assigning a charge to the. fragment that acts as the EO and a O charge to the fragment that acts as the Nu O. (d) On an aldehyde, which carbon is the NuO and which is the EO? Check to make sure this agrees with the charges placed on the synthons in #4c.
Expert Answer:
Related Book For
Posted Date:
Students also viewed these chemistry questions
-
Write the structure of the aldol condensation product of each of the aldehydes in Problem 18.10. One of these aldehydes can undergo aldoladdition, but not aldol condensation. Which one? Why?
-
Write the structure of the aldol condensation product of each of the aldehydes in Problem 18.10. One of these aldehydes can undergo aldol addition, but not aldol condensation. Which one? Why?
-
Write the structures of the aldol condensation products of (a) pentanal; (b) 3-methylbutanal; (c) cyclopentanone.
-
A 60-kHz radio transmitter sends an electromagnetic wave to a receiver 21 km away. The signal also travels to the receiver by another path where it reflects from a helicopter as shown. Assume that...
-
Ang Electronics, Inc., has developed a new HD DVD. If the HD DVD is successful, the present value of the payoff (at the time the product is brought to market) is $30 million. If the HD DVD fails, the...
-
The 25-lb double pulley shown is at rest and in equilibrium when a constant 3.5 lb ??ft couple M is applied. Neglecting the effect of friction and knowing that the radius of gyration of the double...
-
The following balances come from the ledger of Hansi's Home Furniture Factory at 30 June 2025. Hansi's Home Furniture Factory financial year ends on 30 June. During the year the accountant prepared...
-
The following transactions took place during 2012. Record these transactions in journal form. Also, indicate the fund in which each transaction is recorded. 1. The city sold some of its street repair...
-
18.A sine wave is travelling in a medium. The minimum distance between the two particles, always having same speed, is (1) (2)
-
The proposed rates were not in the range the CEO expected given the pricing analysis. The CEO has asked the pricing actuary to verify the total projected loss cost excluding potential large storm...
-
Given the following details, Calculate sales journal, purchases journal, general journal, and then add them to the relevant ledger accounts Year 2006 May 2 Credit sales to E. Kamau "2 Credit...
-
How much will you have in your investment account in 9 years if you initially invest $10,000? The interest rate is 7% annually compounded each quarter.
-
Covington Corporation's comparative balance sheet for current assets and liabilities was as follows: Dec. 31, 20Y2 Dec. 31, 20Y1 Accounts receivable $16,500 $15,800 Inventory 79,000 79,700 Accounts...
-
What is the distinction between cash premise and gathering premise bookkeeping? How does the matching guideline affect budget reports? Make sense of the idea of deterioration and its significance in...
-
Calculate a cost-to-charge ratio for DRG 195 (simple pneumonia and pleurisy without complicating or comorbid condition and major complicating or comorbid condition) using Medicare's MED PAR data (see...
-
Consider Gary's utility function: U(X,Y) = 5 XY, where X and Y are two goods. Which bundle would Gary prefer? Bundle A: X=9 and Y = 6 Bundle B: X 15 and Y = 3
-
A manometer has oil (density 850 kg/m 3 ) is attached to a tank filled with air. If the oil-level difference between the two columns is 45 cm and the atmospheric pressure is 98 kPa, determine the...
-
The swap spread is the difference between the swap rate and the equivalent-maturity Treasury bond yield. Explain why a widening swap spread may be a signal of deteriorating economic conditions. Plot...
-
Suggest an efficient synthesis of m-nitrobenzoic acid from toluene.
-
Write the structure of the major organic product formed in the reaction of 1-pentene with each of the following: (a) Hydrogen chloride (b) Hydrogen bromide (c) Hydrogen bromide in the presence of...
-
For each of the following molecules that contain polar covalent bonds, indicate the positive and negative ends of the dipole, using the symbol v. Refer to Table 1.2 as needed. (a) HCl (b) ICl (c) HI...
-
A proton with an initial speed of \(800,000 \mathrm{~m} / \mathrm{s}\) is brought to rest by an electric field. a. Did the proton move into a region of higher potential or lower potential? b. What...
-
A 1.0-cm-diameter sphere is charged to a potential of \(3400 \mathrm{~V}\). How much charge is on the sphere?
-
a. What is the electric potential at points A, B, and C in Figure P21.16? b. What is the potential energy of an electron at each of these points? c. What are the potential differences \(\Delta...
Study smarter with the SolutionInn App