The following paragraph is the aim of an experiment regarding Cyclodextrin guest-host Chemistry. Rephrase and explain the
Question:
The following paragraph is the aim of an experiment regarding Cyclodextrin guest-host Chemistry.
Rephrase and explain the following paragraph (including terminology, molecules and techniques listed)
This experiment examines host-guest interactions between a small molecule (8-anilino-1-naphthalenesulfonate and Methyl-β-Cyclodextrin (ME β-CD) a derivative of β-CD which has been modified to give a more hydrophobic cavity. ANS displays increased fluorescence intensity in a hydrophobic (non-polar) environment compared to in a polar solvent such as water. Therefore, when
ANS associates with a β-CD molecule, an enhancement in fluorescence can be seen. This binding interaction between the two molecules will be examined in this lab session using fluorescence spectroscopy. An estimate of the binding constants of the complexes will also be examined.