Choose one or more:

A$.$ Ras is bound to Ras$-$GAP.

B$.$ Switch $1$ and switch $2$ regions are in an active conformation.

C$.$ Ras is bound to GTP$.$

D$.$ Ras is bound to GDP$.$

Part $2(1$ point$)$

See Hint

Specific amino acids, including Arg $789$ in Ras$-$GAP and amino acids Gln $61$ and Thr $35$ in Ras, all play an important role in Ras function. Why are these amino acids important?

Choose one:

A$.$ They help Ras bind GTP tightly.

B$.$ They help Ras bind GDP tightly.

C$.$ They help facilitate GTP hydrolysis by Ras.

D$.$ They help downstream signaling by binding to additional signaling proteins.