Colbacin B is a natural product that has the following configuration. It is a potent anti-inflammatory...
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Colbacin B is a natural product that has the following configuration. It is a potent anti-inflammatory agent. It also has a specific rotation of -62º. H Colbacin B A synthetic mixture of Colbacin B and its enantiomer, however, had an observed specific rotation of +18°. (ee) = ([% of major] - [% of minor]) enantiomer; ee = [a]25⁰ H = α Ixc [a]mixture [a]pure enantiomer -x100% Answer the following questions about the synthetic mixture. You may need the equations shown above. a. If the synthetic mixture were a racemic mixture of the natural product shown above and its' enantiomer what would be its specific rotation at 25°C at the sodium D line? b. What is the percent enantiomeric excess of the synthetic mixture? c. What is the percent of the non-natural Coibacin B (i.e. the enantiomer of Coibacin B) in the mixture out to 1 decimal place? Colbacin B is a natural product that has the following configuration. It is a potent anti-inflammatory agent. It also has a specific rotation of -62º. H Colbacin B A synthetic mixture of Colbacin B and its enantiomer, however, had an observed specific rotation of +18°. (ee) = ([% of major] - [% of minor]) enantiomer; ee = [a]25⁰ H = α Ixc [a]mixture [a]pure enantiomer -x100% Answer the following questions about the synthetic mixture. You may need the equations shown above. a. If the synthetic mixture were a racemic mixture of the natural product shown above and its' enantiomer what would be its specific rotation at 25°C at the sodium D line? b. What is the percent enantiomeric excess of the synthetic mixture? c. What is the percent of the non-natural Coibacin B (i.e. the enantiomer of Coibacin B) in the mixture out to 1 decimal place?
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a Cobalcin B has a specific rotation of 62 The enantiomer of Cobalcin B should rotate the ... View the full answer
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