Question: Consider the follow-up study data from the Evans County (Georgia) Heart Disease Study described by Cassels (1971). The data pertain to a cohort of 609
Consider the follow-up study data from the Evans County (Georgia) Heart Disease Study described by Cassels (1971). The data pertain to a cohort of 609 healthy white males between the ages of 40 and 76 who were residents of Evans County in 1960. The cohort was followed for 7 years, after which new cases of coronary heart disease (CHD) were identified. The level of circulating catecholamine (CAT) is the exposure variable of interest (defined as 1 = high and 0 = normal). The purpose of the study was to assess the putative association between CAT (as measured in 1960) and the subsequent 7-year incidence of CHD controlling for other potential confounders. The data are summarized below: High CAT Low CAT CHD 27 44 71 No CHD 95 443 538 122 487 609 All other variables of interest for this example include: AGE: age (in years); CHL: cholesterol level (mg/dl); SMK: smoking status (1 = ever smoked or 0 = never smoked); ECG: electrocardiogram abnormality (1 = yes or 0 = no); DBP: diastolic blood pressure (mm Hg); SBP: systolic blood pressure (mm Hg); HPT: high blood pressure defined as having SBP 160 or DBP 95 (1 = yes
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