1. Data are collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo, the extent of wound healing is measured and the data are shown in the table below. Is there a difference in the extent of wound healing by treatment? Run the appropriate test at a 5% level of significance.

Treatment Percent Wound Healing

0-25% 26-50% 51-75% 76-100%

New compound (n=125) 15 37 32 41

Placebo (n=125) 36 45 34 10

2.Use the data is problem 1 and pool the data across the treatments into one sample of size n=250. Use the pooled data to test whether the distribution of the percent wound healing is approximately normal. Specifically, use the following distribution: 30%, 40%, 20%, and 10%. Run the appropriate test at =0.05.

3.The data shown below was collected in an experiment designed to investigate the impact of different positions of the mother during ultrasound on fetal heart rate. Fetal heart rate is measured by ultrasound in beats per minute. The study includes 20 women who are each assigned to one position and have the fetal heart rate measured in that position. Each woman is between 28 and 32 weeks gestation. Is there a significant difference in mean fetal heart rate by position? Run the test at a 5% level of significance.

Back Side Sitting Standing 140 141 144 147 144 143 145 145 146 145 147 146 141 144 148 149 139 136 144 145