4. 10 pts. Given the reaction below: Acetyl-CoA + oxaloacetate Citrate + CoA-SH AG =...
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4. 10 pts. Given the reaction below: Acetyl-CoA + oxaloacetate → Citrate + CoA-SH AG" = -32.2 kJ/mol Is the forward reaction favored at 18.00 "C? Prove your answer mathematically and report to three significant figures. Cellular concentrations are as follows: [Acetyl-CoA = 4.00 mM]. [oxaloacetate = 3.75 mM]. [citrate=257.2 mM], [CoA-SH= 121 mM] 5. 9 pts. Draw the structure of glutamic acid at pH 8.2 and determine whether it is a Zwitterion at that pH. 6. 6 pts. The structure of histidine is shown below. At what pH range would this structure be the predominate form? Defend your answer. H- Coo -CH₂- NH NH* NH3* 7. You have been told that a buffer is useable within 1 pH unit of its pKa. PIPES buffer has a pka of 6.76. b. 6 pts. Determine the ratio of protonated to deprotonated PIPES at pH 7.76. c. 3 pts. Does PIPES still have a buffering capacity at pH 7.76? Explain your answer. 4. 10 pts. Given the reaction below: Acetyl-CoA + oxaloacetate → Citrate + CoA-SH AG" = -32.2 kJ/mol Is the forward reaction favored at 18.00 "C? Prove your answer mathematically and report to three significant figures. Cellular concentrations are as follows: [Acetyl-CoA = 4.00 mM]. [oxaloacetate = 3.75 mM]. [citrate=257.2 mM], [CoA-SH= 121 mM] 5. 9 pts. Draw the structure of glutamic acid at pH 8.2 and determine whether it is a Zwitterion at that pH. 6. 6 pts. The structure of histidine is shown below. At what pH range would this structure be the predominate form? Defend your answer. H- Coo -CH₂- NH NH* NH3* 7. You have been told that a buffer is useable within 1 pH unit of its pKa. PIPES buffer has a pka of 6.76. b. 6 pts. Determine the ratio of protonated to deprotonated PIPES at pH 7.76. c. 3 pts. Does PIPES still have a buffering capacity at pH 7.76? Explain your answer.
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4 80 AcetylcoA oxalo a crate Citrate COASH For a reaction to be tavo used t... View the full answer
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The Legal Environment of Business A Critical Thinking Approach
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