Design a Synthesis

1. Using the starting material molecule(s) provided, propose a synthesis of the target molecule using as many steps and/or reagents as necessary.

2. Write out your synthesis and include all reagents and/or reaction conditions.

Answers will be graded for a) the feasibility of your synthesis and b) your justification for your proposed synthtic route. You may wish to address the following issues in your response, if they are pertinent to the reaction(s) you propose to employ:

1. Chemoselectivity (why this functional group and not another?)

2. Regioselectivity (why here and not there?)

3. Stereoselectivity (why this stereisomer?)

4. Changes in oxidation state.

OH HO H H Quote II entre . Me MeO + + HEH