Determine whether each situation describes a cryptic self antigen or a novel self antigen.

Cryptic Self Antigen

A protein is denatured when the skin is burned and reaches the lymph node in a linear form to interact with B cells.Press Space to openCryptic Self AntigenNovel Self Antigen

A gene in the skin experiences UV damage, resulting in a few amino acid changes in a protein$$s sequence.Press Space to openCryptic Self AntigenNovel Self Antigen

A liver protein undergoes post$-$translational modifications.Press Space to openCryptic Self AntigenNovel Self Antigen

A B cell processes a self protein through the immunoproteasome following activation by a self antigen.Press Space to openCryptic Self AntigenNovel Self Antigen

Novel Self Antigen