Determine whether the study is an experiment or an observational study, and then identify a major p A study involved 22,071 male physicians. Based on random selections, 11,037 of them were treated because it became clear that aspirin reduced the risk of myocardial infarctions by a substantial amou . . . This is an because the researchers the individuals. What is a major problem with the study? O A. This is a convenience sample with voluntary response, which has a high chance of leading to O B. The results apply only to individuals with heart disease. O C. There is no blinding or replication, which has a high chance of leading to bias. O D. The results apply only to male physicians