Question: Some drugs are metabolised as they pass through the skin, in which case the drug-delivery process is modelled as a diffusion-elimination equation: dc t

Some drugs are metabolised as they pass through the skin, in which

Some drugs are metabolised as they pass through the skin, in which case the drug-delivery process is modelled as a diffusion-elimination equation: dc t 8c = D- 8x - kc (2) where k represents the elimination rate. (g) Non-dimensionalise equation eqn (2). (h) From eqn (2), what dimensions must the elimination coefficient k have? (i) In this situation, the steady-state molar flux J depends on k as well as on Co, D and h (still depending linearly on Co). Use dimensional analysis to determine the functional dependence of J on these three quantities. (j) What restrictions would your result from part (f) impose on the nature of this depen- dence?

Step by Step Solution

★★★★★

3.44 Rating (160 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock

To nondimensionalize the diffusionelimination equation 2 we need to introduce dimensionless variables Lets define the following Let C be the drug concentration in molar units Let 0 C 0 be the initial ... View full answer

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related Law Questions!

The energy per unit area per unit time per unit wavelength interval emitted by a blackbody at a temperature T is given by At a specific temperature, the total power radiated per unit area of the...

A cyclist with a total skin area of 1.5 m2 is riding a bicycle on a day when the air temperature is 20oC and her skin temperature is 34oC. The cyclist does work at about 200 W (moving the pedals) but...

The exitance (power per unit area per unit wavelength) from a blackbody (Box 19-1) is given by the Planck distribution: where _ is wavelength, T is temperature (K), h is Planck's constant, c is the...

You plan to invest $2,000 per year into a retirement account. If you earn a compound annual rate of return of 5%, how many years will it take you to reach a balance of $500,000? 50.14 47.22 51.99...

LYNK BIOTECH: OPEN INNOVATION PROJECT MANAGEMENT July 2020, Singapore. Dr Boon Tiong (David) Tan, Executive Director of Lynk Biotechnologies (Lynk), was deep in thought. Lynk's transdermal...

The conclusion is the question. Request you to please be as elaborate as possible, this is a Strategic Management university paper. Give a complete SWOT and PESTEL analysis of the Case study (SWOT...

respond shortly to this post I choose to do Basal Cell Carcinoma. Risk factors for Basal cell carcinoma are: Chronic sun exposure Radiation therapy Fair skin Increasing age Family history of skin...

Based on the results obtained in problem 35, how much total nicotine is stored directly beneath the patch in the skin and in the fat layers? Problem 35 A nicotine patch is designed to deliver \(24...

Testing a new drug starts with Toxicology tests followed by three stages of clinical trials. At each stage of testing 50% of the drugs fail. The ones that pass a certain stage then proceed to the...

The Veeta Baking Company has a single product known as Veeta Bread. The company uses a process costing system. The Veeta Bread is processed through two departments mixing department and baking...

Define the following interfund transaction terms and explain how each is accounted for and reported by a municipality: (a) interfund reimbursement, (b) interfund loan, (c) interfund services provided...

Please give the step by step solution to the following: TechTown Internet Infrastructure Upgrade The town of TechTown has long been exploring ways to diversify its local economy and attract new...

Access the FASB Accounting Standards Codification at the FASB website (asc.fasb.org). Required: Determine the specific citation for accounting for each of the following items: 1. What disclosures are...

Nikki Gs Corporations 10-year bonds are currently yielding a return of 6.05 percent. The expected inflation premium is 1.00 percent annually and the real risk free rate is expected to be 2.10 percent...

Monitor Muffler sells franchise arrangements throughout the United States and Canada. Under a franchise agreement, Monitor receives $600,000 in exchange for satisfying the following separate...

Able Company issued $600,000 of 9 percent first mortgage bonds on January 1, 20X1, at 103. The bonds mature in 20 years and pay interest semiannually on January 1 and July 1. Prime Corporation...

Access the FASB Accounting Standards Codification at the FASB website (asc.fash.org). Required: Determine the specific citation for accounting for each of the following items: 1. What alternative...

what is the answer to this? .. Question 18 - W2.5 - Quiz - C x * Chat Thread X 25 ezto.mheducation.com/ext/map/index.html?_con=con external_browser=0...

An investment under consideration has a payback of five years and a cost of $ 1,200. If the required return is 20 percent, what is the worst- case NPV? Explain fully. Source: R. Watts.

Pool Scrubbers manufactures three different models of swimming pool cleaners ( 710, 720, and 830). These are sophisticated computer- controlled, programmed cleaners that scrub and vacuum the pools...

Tilist Golf is a premier producer of golf clubs and golf balls. The Ball Division makes two types of balls: a professional ball (the Masters) played by professional and top amateur players, and a...

For the population in Example 2.2, find the sampling distribution of for a. an SRS of size 3 (without replacement) b. an SRSWR of size 3 (with replacement). For each, draw the histogram of the...

Mayr et al. (1994) took an SRS of 240 children who visited their pediatric outpatient clinic. They found the following frequency distribution for the age (in months) of free (unassisted) walking...

For the population in Example 2.2, consider the following sampling scheme: a. Find the probability of selection i for each unit i. b. What is the sampling distribution of =8?