Question: Discuss the cellular pathophysiological processes involved in Marcus's disease. How do these relate to his presenting symptoms? Identify the genetic mutation responsible for this disease

  • Discuss the cellular pathophysiological processes involved in Marcus's disease. How do these relate to his presenting symptoms?
  • Identify the genetic mutation responsible for this disease and its mode of inheritance.
  • Explain how sickle cell disease affects the immune system.
  • Describe how current treatments, such as hydroxyurea, target the cellular alterations of the disease.
  • What patient-specific or culturally sensitive education might an APRN provide to help Marcus adhere to his treatment plan?

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