Discuss the methodologies used for hydrologic modeling and simulation, and evaluate their effectiveness in predicting water flow, distribution, and quality under various scenarios. Analyze the challenges associated with integrating these theoretical models into practical applications, such as accounting for climate variability, land use changes, and urbanization. Explore the role of innovative technologies, such as remote sensing and geographic information systems $($GIS$),$ in enhancing the accuracy and reliability of water resources management. Additionally, consider the potential benefits and limitations of adopting a holistic, systems$-$based approach to water resources engineering in achieving sustainable and resilient water infrastructure.