Discussion Board

Pick a different drug test data from the Internet (any drug or prescribed medication) similar to the Zocor and Gemfibrozil in Week 2 Lecture notes and comment on their statistical analysis to justify the efficacy of the drug. youcan also the JAMA article in theweek 2 folder. Use Examples http://www.medicinenet.com/high_blood_pressure_medication/article.htmorhttp://www.drugs.com/condition/hyperlipidemia.html

these two table example from the data that you can get from the website

Table 2. Primary Outcome of Death or Disability OR Adjusted for Center Caffeine Placebo and Patient Group, Group, P Characteristics Outcome No./Total (%) No./Total (%) Value (95% cha Composite Death or disability 176/833 (21.1) 200/807 (24.8) 09 0.86 (0.67-1.09) Components Death before 5 yb 59/867 (6.8) 58/837 (6.9) 92 1.03 (0.69-1.52) Motor impairment .d 13/803 (1.6) 21/773 (2.7) .20 0.63 (0.31-1.28) Cognitive impairment c.f 38/768 (4.9) 38/750 (5.1) .89 1.11 (0.68-1.80) Behavior problem.9 42/773 (5.4) 53/748 (7.1) .18 0.78 (0.51-1.20) Poor general health 32/805 (4.0) 33/775 (4.3) .75 0.95 (0.57-1.58) Severe hearing loss 22/798 (2.8) 25/773 (3.2) 58 0.91 (0.51-1.64) Bilateral blindness 7/792 (0.9) 7/763 (0.9) .94 1.04 (0.35-3.02) Abbreviation: OR, odds ratio. "The odds ratio has been adjusted for the gestational age and sex of the infant, the mothn of corticosteroids, and multiple births, in addition to center. This outcome is for all children whose vital status was known at a corrected age of 5! "Data for this outcome exclude children who died before the scheduled tests and thosthis outcome may include children who had incomplete assessments at 5 years. "Motor impairment was defined as a Gross Motor Function Classification System level The odds ratio for this outcome was not adjusted for center because there were too f Cognitive impairment was defined as a Full Scale IQ of less than 70. "Behavior problem was defined as a Total Problem T score of greater than 69 for the FTable 2. Primary Outcome of Death or Disability OR Adjusted for Center Caffeine Placebo OR Adjusted and Patient Group, Group, Unadjusted for Center P Characteristics Outcome No./Total (%) No./Total (%) OR (95% CI) (95% CI) Value (95% cha Composite Death or disability 176/833 (21.1) 200/807 (24.8) 0.81 (0.65-1.02) 0.82 (0.65-1.03) .09 0.86 (0.67-1.09) Components Death before 5 yb 59/867 (6.8) 58/837 (6.9) 0.98 (0.67-1.43) 0.98 (0.70-1.43) .92 1.03 (0.69-1.52) Motor impairment ",d 13/803 (1.6) 21/773 (2.7) 0.59 (0.29-1.18) 0.59 (0.29-1.18) .20 0.63 (0.31-1.28) Cognitive impairment ,f 38/768 (4.9) 38/750 (5.1) 0.98 (0.62-1.55) 0.97 (0.61-1.55) 89 1.11 (0.68-1.80) Behavior problem9 42/773 (5.4) 53/748 (7.1) 0.75 (0.50-1.14) 0.75 (0.49-1.15) .18 0.78 (0.51-1.20) Poor general health 32/805 (4.0) 33/775 (4.3) 0.93 (0.57-1.51) 0.92 (0.56-1.52) 75 0.95 (0.57-1.58) Severe hearing loss 22/798 (2.8) 25/773 (3.2) 0.85 (0.47-1.52) 0.85 (0.47-1.52)e 58 0.91 (0.51-1.64) Bilateral blindness 7/792 (0.9) 7/763 (0.9) 0.96 (0.34-2.75) 0.96 (0.34-2.75) .94 1.04 (0.35-3.02) Abbreviation: OR, odds ratio. The odds ratio has been adjusted for the gestational age and sex of the infant, the mother's education at the assessment, antenatal administration of corticosteroids, and multiple births, in addition to center. "This outcome is for all children whose vital status was known at a corrected age of 5 years. "Data for this outcome exclude children who died before the scheduled tests and those who were alive but were not tested. However, data for this outcome may include children who had incomplete assessments at 5 years. "Motor impairment was defined as a Gross Motor Function Classification System level of greater than 2. "The odds ratio for this outcome was not adjusted for center because there were too few events. "Cognitive impairment was defined as a Full Scale IQ of less than 70. " Behavior problem was defined as a Total Problem T score of greater than 69 for the Parent Form of the Child Behavior Checklist