Does similarity in sequence prove similarity in function? Explain.

What are other techniques you can use $($computational and lab techniques$)$ to determine if two proteins have similar functions?

How can BLAST help you identify the active site of your POI? $($What kind of homolog is the program using for comparison?

Describe $2$ advantages and $2$ disadvantages specific to the BLAST program$/$database

How can SPRIIE help you identify the active site of your POI? $($What kind of homolog is the program using for comparison?

Describe $2$ advantages and $2$ disadvantages specific to the SPRIIE program$/$datahase